Before starting to work on your Pine configuration, you must make sure that the Exchange Server is configured correctly. This is where your SysAdmin comes in to play. You need to make sure the IMAP, SMTP, and LDAP services are all running. These services could potentially be running on separate servers, so you need to consult your SysAdmin.
On Exchange Server 5.5, IMAP and LDAP are installed and running in the default installation. SMTP has to be installed separately, and comes in an add-on package called Microsoft Exchange Connector, specifically for sending mail on the Internet.
NOTE: You can manually check to see if these services are running by telneting to their respective ports. (ie. IMAP:143, SMTP:25, and LDAP:389)